“Engineering Human Tissues for Regenerative Medicine and Study of Disease”
Mikati Foundation Professor of Biomedical Engineering
Professor of Medical Sciences (in Medicine)
Director, Laboratory for Stem Cells and Tissue Engineering
Columbia University, New York
Friday, February 3, 2017
Wishnick Hall, Room 113
Tissue engineering is becoming increasingly successful with authentically representing the actual environmental milieu of the development, regeneration and disease. A classical paradigm of tissue engineering is related to the integrated use of human cells, biomaterial scaffolds (structural and logistic templates for tissue formation) and bioreactors (culture systems providing environmental control, molecular and physical signaling) in regenerative medicine. Living human tissues can be bioengineered from the autologous stem cells, and tailored to the patient and the medical condition being treated.
More recently, the same principles are being successfully applied to the patient-specific “organs on a chip” platforms designed to recapitulate some aspects of human physiology. This talk discussed some recent advances in regenerative engineering and modeling of disease using functional human tissues grown in lab.