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2017 Pritzker Distinguished Lecturer Gordana Vunjak-Novakovic

“Engineering Human Tissues for Regenerative Medicine and Study of Disease”

Gordana Vunjak-Novakovic
Mikati Foundation Professor of Biomedical Engineering
Professor of Medical Sciences (in Medicine)
Director, Laboratory for Stem Cells and Tissue Engineering
Columbia University, New York

Friday, February 3, 2017 at 1:50 p.m.
Wishnick Hall, Room 113

Tissue engineering is becoming increasingly successful with authentically representing the actual environmental milieu of the development, regeneration and disease. A classical paradigm of tissue engineering is related to the integrated use of human cells, biomaterial scaffolds (structural and logistic templates for tissue formation) and bioreactors (culture systems providing environmental control, molecular and physical signaling) in regenerative medicine. Living human tissues can be bioengineered from the autologous stem cells, and tailored to the patient and the medical condition being treated.

More recently, the same principles are being successfully applied to the patient-specific “organs on a chip” platforms designed to recapitulate some aspects of human physiology. This talk will discuss some recent advances in regenerative engineering and modeling of disease using functional human tissues grown in lab.

This event is free and open to the Illinois Tech community.

2016 Pritzker Distinguished Lecturer Nicholas A. Peppas

Nicholas Peppas

"Intelligent Nanoscale Biopolymers for Recognitive and Responsive Delivery of Drugs, Peptides, and Proteins"

Nicholas A. Peppas, Sc.D.
Cockrell Family Regents Chair in Engineering #6
Professor of Biomedical Engineering, Chemical Engineering and Pharmacy
Director, Institute for Biomaterials, Drug Delivery, and Regenerative Medicine
University of Texas at Austin

Friday, February 19, 2016 at 1:50 p.m.
Wishnick Hall, Room 113

Engineering the molecular design of intelligent biopolymers and especially hydrogels by controlling recognition and specificity is the first step in coordinating and duplicating complex biological and physiological processes. We address design and synthesis characteristics of nover crosslinked networks capable of protein release as well as artificial molecular structures capable of specific molecular recognition of biological molecules. Recent developments in protein delivery have been directed toward the preparation of targeted formulations for protein delivery to specific sites, use of environmentally responsive polymers to achieve pH- or temperature-triggered delivery, usually in modulated mode, and improvement of the behavior of their mucoadhesive behavior and cell recognition. Molecular imprinting and microimprinting techniques, which create stereo-specific three-dimensional binding cavities based on a biological compound of interest can lead to preparation of biomimetic materials for intelligent drug delivery, drug targeting, and tissue engineering. We have been successful in synthesizing novel glucose-binding molecules based on non-covalent directed interactions formed via molecular imprinting techniques within aqueous media.

This event is free and open to the Illinois Tech community.

2015 Pritzker Distinguished Lecturer Martin L. Yarmush

"New Approaches to Mesenchymal Stem Cell Therapy"

Martin L. Yarmush, M.D., Ph.D.
Paul and Mary Monroe Chair, Distinguished Professor of Biomedical Engineering
Rutgers University

Friday, April 24, 2015 at 1:50 p.m.
Wishnick Hall, Room 113
Reception to follow

Recently, there has been a paradigm shift in what is considered to be the therapeutic promise of mesenchymal stem cells (MSCs) in diseases of vital organs. Originally, research focused on MSCs as a source of regenerative cells through the differentiation of transplanted cells into lost cell types. It is now clear that trophic modulation of inflammation, cell death, fibrosis, and tissue repair are primary mechanisms of MSC therapy. This has been clarified in studies where delivery of growth factors, cytokines, and other signaling molecules secreted by MSCs is often sufficient to obtain the therapeutic effects. In this presentation, examples of MSC therapy in disease models of vital organs using models of acute liver failure, acute renal injury, and spinal cord injury will be described.

This event is free and open to the Illinois Tech community.

2014 Pritzker Distinguished Lecturer James J. Collins

Life Redesigned: The Emergence of Synthetic Biology

Howard Hughes Medical Institute
Department of Biomedical Engineering and Center of Synthetic Biology, Boston University
Wyss Institute for Biologically Inspired Engineering, Harvard University

Friday, April 11, 2014 at 1:50 p.m.
Wishnick Hall 113
Reception to follow

Synthetic biology is bringing together engineers, physicists, and biologists to model, design, and construct biological circuits out of proteins, genes, and other bits of DNA, and to use these circuits to rewire and reprogram organisms. These re-engineered organisms are going to change our lives in the coming years, leading to cheaper drugs, rapid diagnostic tests, and targeted therapies to attack “superbugs.” In this talk, we highlight recent efforts to create synthetic gene networks and programmable cells, and discuss a variety of synthetic biology applications in biocomputing, biotechnology, and biomedicine.

This event is free and open to the Illinois Tech community.

Department of Biomedical Engineering Ph.D. Candidate: Shuo Yang

Investigation of von Willebrand Factor (VWF) Degradation under Controlled Shear Exposure


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Robert A. Pritzker Endowed Chair in Engineering

Vincent Turitto, director of the Pritzker Institute of Biomedical Science and Engineering, was invested as the Robert A. Pritzker Endowed Chair in Engineering on August 10, 2011 in a private ceremony for the Pritzker and Turitto families.

Karen Pritzker funded the chair in honor of her father and University Regent Robert A. Pritzker, who graduated from Illinois Tech with an industrial engineering degree in 1946 and provided vision and leadership to the university for more than 50 years. Pritzker's foresight in establishing the Pritzker Institute of Biomedical Science and Engineering at Illinois Tech in 1980 has helped bring the university to the forefront of medical engineering research.

Turitto, who leads the Pritzker Institute, has made significant contributions to the expanding body of biomedical engineering research at Illinois Tech over the past decade. In addition to serving as director of the Pritzker Institute and chair of the Department of Biomedical Engineering, Turitto has authored more than 100 publications, received numerous research grants, and helped establish critical relationships between Illinois Tech and other medical research institutions.

"We are grateful to the Pritzker family for their many extraordinary contributions to the future of this university," said President John Anderson. "Endowed chairs are vital in ensuring retention of our best and brightest professors."

Posted 08/25/11

Pritzker Distinguished Lecture

"Building a 'Body-On-A-Chip': Toward Better Drug Development"

Michael L. Shuler
Cornell University

Thursday, October 13, 2011 at 8 a.m.
Ballroom ABC at the Connecticut Convention Center
100 Columbus Boulevard, Hartford, Connecticut

Michael Shuler, chair of biomedical engineering and professor of chemical engineering at Cornell University, was awarded a 2011 Robert A. Pritzker Distinguished Lectureship. Shuler will present at the annual Biomedical Engineering Society meeting on Thursday, October 13.

The text of the lecture will be published in the Annals of Biomedical Engineering.

For more information, click here

Pritzker Seminar Series

Neutrons and Their Application to Biomimetic Systems

John Katsaras
Oak Ridge National Laboratory

Friday, October 28, 2011 at 3:30 p.m.
Illinois Institute of Technology
University Technology Park, Conference Room CD

Abstract:

Neutron and X-ray scattering are two of the most powerful structural determination techniques available today. Although many are familiar with the exploits of atomic resolution X-ray crystallography—in particular, protein crystallographythese techniques also have applications in polymer science, colloid chemistry, and materials science. Neutron scattering is ideally suited for the study of biological materials rich in hydrogen because of its ability to interact differentially with hydrogen and its isotope deuterium. It is also one of the few techniques capable of characterizing structure, dynamics, and interfacial relationships in complex biological systems. With the suite of neutron-scattering instruments suitable for the study of biological materials (e.g., small-angle scattering, diffraction, spectroscopy, and reflectometry) in place at the Spallation Neutron Source (SNS) and the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory, it is now possible to address questions of interest to the biological and medical communities. Today's seminar will give a brief overview of the neutron's history, its methods of production, and recent applications of neutron scattering to biologically relevant materials (e.g., cholesterol in PUFA bilayers; determination of lipid areas; neutrons and MD simulations).

BME's Sophia Pilipchuk Wins BMES 2011 Undergraduate Student Award

Sophia PilipchukIllinois Tech biomedical engineering undergraduate senior Sophia Pilipchuk was named as one of five recipients of the Biomedical Engineering Society (BMES) Undergraduate Student Award, to be presented in October at the BMES Annual Business Meeting in Hartford, Connecticut.

Up to eight undergraduate students are selected from around the country on the basis of originality, significance, thoroughness of design analysis, and performance evaluation. Pilipchuk performs research on "Crosslinking of Tissue Derived Hydrogels" with BME doctoral student Marcella Vaicik and Associate Professor Eric Brey.

Undergraduate awards include a certificate, a complimentary registration for the Annual Meeting, and a stipend to assist with travel expenses.

Biomedical Engineering Department

Pritzker Seminar Series

November 15, 2010 at 1 p.m.

Impact of blood flow and chemical nature of vessel wall lesions on thrombus formation and anti-thrombotic efficacy.

Kjell S. Sakariassen, KellSa s.a.s., Italy

Location University Technology Park at Illinois Tech

Engineering Center for Diabetes Research and Education (ECDRE)


Omaditya “Goldey” Khanna, a senior CHBE student, won second place in the fall 2009 Annual Meeting of the Biomedical Engineering Society's research competition. His talk, “The Synthesis of Multilayered Alginate/Poly-L-Ornithine/Alginate Microcapsules and the Sustained-Release of Fibroblast Growth Factor-1 from the Outer Alginate Layer," conducts research with BME graduate student Monica Moya and BME Associate Professor Eric Brey.

Khanna published three peer-reviewed journal articles based on work performed in Brey's lab in 2010. Khanna was supported as a Ross Scholar during the summer of 2009.

View ECDRE